ABSTRACT
Background. The importance of physical activity (PA) for maintaining and improving health status increases with each passing day. Objectives. The present study aimed to examine the effects of PA and nutritional education programs applied to 12th-grade students on body mass index (BMI), PA level, and eating habits during the COVID-19 pandemic. Methods. One hundred fifty-nine 12th grade students were randomly assigned to the experimental group (EG) (n=87, 42 male and 45 female) and control group (CG) (n=72, 39 male and 33 female). At first, physical characteristics, PA level, and eating habit questionnaires were completed by students. Then, EG received a single session face-to-face PA and healthy nutrition-themed programs. After an 8-week follow-up, questionnaires were completed by students again. Also, the number of daily steps of EG was recorded during the 8-week follow-up. Differences between pre and post-BMI, PA level, and eating habits of the groups were analyzed using the mixed model ANOVA test. Results. Results showed that educational programs had a positive effect on BMI, PA level, and eating habits of EG (p<.05). There was no improvement in CG (p>0.05). Qualitative findings of EG revealed that the educational program is a beneficial process not only for a short period but also for a lifelong learning structure. Conclusion. In conclusion, PA and healthy nutrition-themed educations are effective methods to improve youths' awareness to be more active and healthier in their daily life, including during the pandemic processes.
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Background and Aim: Cardiovascular manifestations are common (35-100%) in multisystem inflammatory syndrome in children (MIS-C), including ventricular dysfunction, shock, coronary artery dilation, pericardial effusion and conduction abnormalities. Our study aimed to analyse cardiovascular involvement in our patients with MIS-C treated in our hospital. Method(s): The retrospective cohort study included all patients with MIS-C treated from April 2020 to December 2021 in the Mother and Child Health Institute of Serbia. In every case, cardiovascular manifestations were analysed: ventricular dysfunction, coronary artery dilatation, pericardial effusion, shock and ECG changes. Result(s): The study included 77 patients, 45 boys and 32 girls, aver-age years of age 9.3 +/- 4.8. Elevated cardiac troponin I and pro-BNP were observed in 35.9% and 87.8% of patients, respectively. Myocardial dysfunction was observed in half of our patients (50.6%), with an average ejection fraction of 50.5 +/- 8.9%. Children older than 10 years had 4 times higher chances for myo-cardial dysfunction (OR 4.3, 95%CI 1.6-10.8;p = 0.003). Shock syndrome had 21.1% of children on admission, while 5.3% devel-oped shock during the in-hospital stay. Transient coronary artery (CA) dilatation was observed in 6.5% of patients;left CA in 3 pts (Z score +2,95 +/- 0.3), right CA in one patient (Z score +2), and in one LCA and RCA (RCA Z score 2.6). Transient CA dilatations were observed only in patients with KD-like clinical presentation (5/54 pts). Mild pericardial effusion with spontaneous resolution was detected in 28.6% of children, while one female adolescent had severe pericardial effusion with threatening cardiac tamponade. On the standard ECG, 53% of children had negative T wave in inferior or/and precordial leads averagely on day 2 (IQR 1-3 day);transient QTc prolongation was registered in 46% of patients, averagely on day 7 (IQR 5-9). Sinus bradycardia and coronary rhythm were registered in 42.1% of patients, while premature ven-tricular beats were observed in 2.7% of pts. left ventricle thrombus was detected in one patient with normal echocardiography find-ing. In this patient, increased activity of Factor VIII and XII was proven. Conclusion(s): Cardiac manifestations are common and potentially life-threatening in MIS-C and should be assessed for at presenta-tion and during the clinical course as indicated.
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Background and Aim: Mixed shock in multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 is con-sequence of acute heart failure, inflammation-induced vasodilation and potential volume loss. Method(s): Retrospective analysis included 25 patients (7 girls) with MIS-C-related combined shock, treated in period from April 2020 to December 2021. Result(s): Mean age of patients was 12.6 +/- 4.0 years. Admission was 6.1 +/- 1.6 days after symptoms onset. Systemic inflammatory response was manifested with neutrophilia (10.7 +/- 4.2 x109/), lymphopenia (1.1 +/- 0.7 x109/L), elevated CRP (220.9 +/- 86.1 mg/L), ferritin (684.5 +/- 549.5 mug/L) and D-dimer (1528 +/- 1254 ng/mL). One third of patients had acute kidney injury with glomerular filtration rate of 64 +/- 22 mL/min/1.73 m2 and urea level of 16.0 +/- 8.4 mmol/L. All patients had acute heart failure with ejection fraction 47.2% +/- 7.7% and fractional shortening 23.6% +/- 4.9%, 92% of patients had NTproBNP gt;1500 pg/mL and 58% had elevated troponin I (1.34 +/- 1.47 ng/mL). Z-scores for end-diastolic left ventricle, interventricular septum and pos-terior wall diameters were 0.7 +/- 1.1, 1.7 +/- 1.3 and 0.6 +/- 0.7 respectively. All patients had mild/moderate mitral regurgitation, and 60% had mild pericardial effusion. Inotropes, administered during first 3.7 +/- 1.6 days, were divided in three groups: 1) dop-amine (n = 14), 2) dobutamine + dopamine (n = 5), 3) milrinone +/- dopamine (n = 6). Additional treatment included diuretics and captopril. Total fluid balance (including insensible loss of 300 mL/m2/day) through days 1-7 was +860 mL/m2, +128 mL/m2,-108 mL/m2,-36 mL/m2,-306 mL/m2,-335 ml/m2,-298 ml/m2 (total-95 ml/m2). Methylprednisolone/intravenous immuno-globulin and low-molecular-weight heparin/acetylsalicylic acid were administered and fever persisted 1.2 days averagely. Oxygen supplementation was needed in 71% of patients. Transitory bradycardia was noticed and there was no difference in heart rate between treatment groups. Profound hypotension was revealed on admission and correction differed regarding treat-ment (p lt;0.05) (Figure 1). All patient survived with clinical improvement (one had mechanical ventilation, and one had stroke). Conclusion(s): Mixed shock is the most severe manifestation of MIS-C, and treatment of heart failure should be combined with cau-tious fluid resuscitation.
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Introduction Diabetes mellitus patients are a vulnerable group of people who are prone to getting infected with severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). The virus has a high binding affinity to angiotensin-converting enzyme 2 receptor, which allows efficient host cell entering, prolonged virus retention, and a possibility of insulin resistance and ketoacidosis development. Case outline We describe a case of a 20-year-old patient with a past medical history of type 1 diabetes mellitus who presented with bilateral COVID-19 pneumonia. Initially, treatment with polyvitamin therapy, corticosteroids, tocilizumab, and convalescent plasma did not improve the patient's condition, but might have led to the worsening of the underlying disease, high blood glucose level, and ketoacidosis. Patient developed a rapid progression of the disease and severe pneumonia that required intubation and mechanical ventilation. Intravenous immunoglobulin (IVIg) was administrated in order to suppress a hyperactive immune response through its immunomodulatory effect. Forty-eight hours later, respiratory gas exchange was improved, almost complete regression of changes in the lungs was seen, normalization of metabolic and gas exchange parameters was detected. After 14 days of hospitalization, the patient was discharged in good general condition. Conclusion COVID-19 complicated by diabetes mellitus leads to a poor outcome of the disease, but antiviral and anti-inflammatory activity of IVIg suggests that it may be a useful therapeutic agent in cases of COVID-19. In the presented case, the application of IVIg led to a rapid improvement in the patient's condition.
ABSTRACT
Using e-learning and social media has become a common part of students' academic lives in many sciences, including sport sciences. The purpose of this research study was to identify attitudes and preferences of students in sports science concerning the use of e-learning and social media at the University of Novi Sad. The present study was included respondents (N=297) from the Faculty of Sport and Physical Education at the University of Novi Sad from all levels of studies. The attitudes and preferences of the use of e-learning and social media were measured with three separate parts: (1) General information (8 items);(2) use of different genres of social media in teaching (28 items);(3) e-learning in the field of sports studies (13 items), and descriptive statistics (frequencies) were used to describe the basic features of the data. The results showed that participants mostly use Facebook (44.4% of students), Viber (66%), and WhatsApp (56.6%) to contact peer students for study in the context of learning purposes. In comparison, they do not use LinkedIn (1.3%), Twitter (0.3%) or Skype (4%). From another side, the students mostly share their messages via Viber and WhatsApp in the form of various questions (67% via Viber;62.6% via WhatsApp), video messages (20.5%;25.3%), screenshots of their screen (21.2%;27.6%), various links (23.2%;25.3%), comments on a current topic (22.2%;22.2%). In the participants' opinion (81.5%), the teaching process has been set back by the coronavirus pandemic. In contrast, the students experienced the pandemic's positive effect as an improvement in e-learning (51.2% of students). They shared the opinion that virtual teaching is not as effective as traditional teaching (85.2%). The theoretical and practical applications of these results are discussed. © 2021 Montenegrin Sports Academy. All rights reserved.